8.1.2. Immune Pathogenesis of Bullous Autoimmune Disorders. Pemphigus and pemphigoid are considered to be pro- totypic bullous disorders based on their
Bullous systemic lupus erythematosus (BSLE) is a rare subset of systemic lupus erythematosus (SLE) associated with autoimmunity to type VII collagen.1 BSLE is an autoimmune-mediated, chronic, widespread, nonscarring, subepidermal blistering skin disease occurring in patients with SLE. In 23% of patients with SLE, cutaneous involvement is the initial manifestation. TWEAK/Fn14 Activation Contributes to the Pathogenesis of ... TWEAK participates in various cellular effects by engaging its receptor of Fn14. Increased levels of soluble TWEAK are associated with systemic autoimmunity in patients with lupus erythematosus, rheumatoid arthritis, or dermatomyositis. However, the role of TWEAK in bullous pemphigoid (BP) remains unknown. In this study, we found an elevated serum level of TWEAK and a positive correlation Bullous pemphigoid | DermNet NZ Bullous pemphigoid occurs equally in males and females. There is an association with human leukocyte antigen (HLA) indicating a genetic predisposition to the disease. It is more prevalent in elderly patients with neurological disease, particularly stroke, dementia and Parkinson disease.
Pathogenesis of epidermolysis bullosa acquisita, an ... pemphigus vulgaris, bullous pemphigoid and epidermolysis bullosa acquisita (EBA), and these have provided insights into the pathogenesis of various ADBs that suggest possible new treatment strategies. However, the fundamental mechanisms in disruption of immune-tolerance are still unknown. EBA shows autoimmunity to type Bullous pemphigoid: Etiology, pathogenesis, and inducing ... Bullous pemphigoid (BP) is an autoimmune blistering disease typically affecting the elderly. The name bullous pemphigoid itself is a pleonasm as pemphigoid is derived from Greek and means form of a blister (pemphix, blister, bulla, and eidos, form).Even so, the redundant adjective bullous enables to distinguish it from other diseases that also belong to the group of pemphigoids, such as The pathogenesis of bullous skin diseases - PDF Free Download
Bullous pemphigoid is an uncommon skin disease characterized by tense blisters on the surface of the skin. Occasionally, the inner lining tissue of the mouth, nasal passages, or conjunctivae of the eyes (mucous membrane tissue) can be involved. Bullous pemphigoid - Aetiology | BMJ Best Practice Autoimmune sub-epidermal blistering skin diseases include the bullous pemphigoid group of diseases (bullous pemphigoid, pemphigoid gestationis, lichen planus pemphigoides, linear IgA disease, cicatricial pemphigoid, and anti-p200, anti-p105, and anti-p450 pemphigoid), epidermolysis bullosa acquisita, and dermatitis herpetiformis. Frontiers | The Intersection of IgE Autoantibodies and ... Bullous pemphigoid (BP) is an autoimmune blistering disease characterized by autoantibodies targeting cellular adhesion molecules. While IgE autoantibodies are occasionally reported in other autoimmune blistering diseases, BP is unique in that most BP patients develop an IgE autoantibody response. It is not known why BP patients develop self-reactive IgE and the precise role of IgE in BP Bullous pemphigoid in infants: characteristics, diagnosis ...
Jul 01, 2013 · Read "Bullous pemphigoid: Etiology, pathogenesis, and inducing factors: Facts and controversies, Clinics in Dermatology" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. Role of physical factors in the pathogenesis of bullous ... Jul 15, 2015 · Bullous pemphigoid (BP) is an autoimmune subepidermal blistering disease affecting mainly the elderly. The subtype of the disease induced by physical agents represents a rare and, therefore, insufficiently characterized form. Peristomal and Generalized Bullous Pemphigoid in Patients ... Dec 12, 2012 · Abstract Bullous pemphigoid (BP) is a blistering disorder of the skin and mucosa that may coexist with inflammatory bowel disease (IBD). The authors’ experiences with peristomal and generalized BP in five patients (three with ulcerative colitis [UC] post colostomy surgery and two with Crohn’s disease [CD] post ileostomy surgery, time since surgery 5 to 20 years) is described.
Pembrolizumab-induced bullous pemphigoid - JAAD Case Reports
